I don't understand either. I don't have a machine to test right now, but I've played DOOM, Monkey Island, Wolfenstein among others and I have sound selecting the proper default IRQ ("5" I think) and DMA ("1" I think). I don't have additional drivers installed and neither the "SET BLASTER=" variable in AUTOEXEC.BAT.
For mouse driver I use CuteMouse.
For transferring data I use the painful method of copying everything to a ISO file then do XCOPY. :P
Every game comes with a really nice README.TXT file that helps you solve any issue you may encounter with the game you're trying to run. That's how PC Master race evolved and console peasants are afraid of touching a keyboard since then.
P.S: I'm talking in a humorous manner, don't take it as a offense. I've always preferred consoles over PCs, but then I found out you can't carry your saves anymore. Retrocompatibility is now nonexistent. Everything is internet protected or console locked. Keyboard/mouse is more precise, but you can use a joystick if you want to. To name a few.