Along with MAME and all its fork, NegaMAME 0.221-1 is also ready for download. Go grab it at http://babelsoft.net/products/negamame.htm
This MAME derivative has been designed to be used with the front-end Negatron in order to have complete access to all the machine configuration options within Negatron, especially useful for emulated computers and consoles.
This is quite irrelevant for emulated arcade games though. If you only play arcade games, you can simply use Negatron with regular MAME.
Note: 0.221-1 must be understood as the 1st version of NegaMAME synchronised with MAME v0.221. If other issues arise with this version, I would release a v0.221-2