NESiCA doesn't seem like it would be that difficult to crack, once someone puts their mind to it, and has the resources they need.
I think the underlying problem would be how important points/player rankings are. Although that would seem like a more trivial aspect to emulate/duplicate (on a private server) or in a local file state.
The sad part for MAME would be them wanting to resurrect ALL their old titles and put it on the NESiCA platform. Space Invaders for example.